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Lipids (Intro, Structure, and Function)
- Lipids: Intro / Overview
- Free Fatty Acids: Intro and Properties
- Free Fatty Acids: Nomenclature and Convention
- Triacylglycerols / Triglycerides
- Membrane Lipids: Intro
- Membrane Lipids: Glycerophospholipids
- Membrane Lipids: Glycerophospholipids with Ether Linkages (Plasmologens and PAF)
- Membrane Lipids: Sphingolipids
- Membrane Lipids: Sphingolipids (examples)
- Sterols / Steroids: Intro / Overview
- Eicosanoids: Intro / Overview [ free YouTube snippet | full free sample video ]
- Dietary Lipids: Digestion and Absorption (Part 1 of 3) - Digestion [ free YouTube snippet | full free sample video ]
- Dietary Lipids: Digestion and Absorption (Part 2 of 3) - Absorption
- Dietary Lipids: Digestion and Absorption (Part 3 of 3) - Clinical Correlate: Malabsorption
Triglyceride / Triacylglycerol Breakdown (Lipolysis) and Fatty Acid Breakdown
- Intro / Overview
- Triacylglycerol / Triglyceride Mobilization and Fatty Acid Activation
- Carnitine-Mediated Transport of Acyl-CoA - "Carnitine Shuttle"
- Clinical Correlate: Carnitine Deficiency and Carnitine as a Supplement
- Beta (β) Oxidation (for an Even-Numbered, Saturated Fatty Acid)
- Beta (β) Oxidation (for an Even-Numbered, Saturated Fatty Acid) - ATP Energy Calculation
- Beta (β) Oxidation (for an Odd-Numbered, Saturated Fatty Acid)
- Beta (β) Oxidation (for an Odd-Numbered, Saturated Fatty Acid) - ATP Energy Calculation
- Beta (β) Oxidation (for an Unsaturated Fatty Acid) [ free YouTube snippet | full free sample video ]
- Beta (β) Oxidation (for an Unsaturated Fatty Acid) - ATP Energy Calculation
- Beta (β) Oxidation in Peroxisomes, Zellweger Syndrome, Adrenoleukodystrophy
- Alpha (α) Oxidation in Peroxisomes, Refsum's Disease
- Omega (ω) Oxidation
- Clinical Correlate: Medium Chain Acyl-CoA Dehydrogenase (MCAD) Deficiency
Ketone Bodies
- Intro / Overview
- Ketone Body Synthesis (Ketogenesis)
- Ketone Body Breakdown (Ketolysis) -- Ketone Bodies Used as a Fuel Source (Oxidation of Ketone Bodies)
- Diabetes, Starvation, and Ketoacidosis - Overview
Triglyceride / Triacylglycerol Synthesis (Lipogenesis) and Fatty Acid Synthesis
- Intro / Overview
- Transport of Acetyl-CoA from Mitochondria to Cytosol
- Activation of Acetyl-CoA to Malonyl-CoA
- Fatty Acid Synthase Complex
- Palmitate Synthesis
- Side-by-Side Comparison with β-Oxidation
- Palmitate Synthesis - Summary and Stoichiometry
- Regulation of Fatty Acid Synthesis
- Hormonal Control of Fatty Acid Synthesis
- Clinical Correlate: Excess Alcohol Consumption and Fatty Liver
- Fatty Acid Synthesis: Elongation
- Fatty Acid Synthesis: Desaturation
- Triglyceride / Triacylglycerol Synthesis (Lipogenesis)
Glycerophospholipids and their Metabolism
- Glycerophospholipids: Intro / Overview [copy from Lipids chapter]
- Glycerophospholipid Synthesis: Intro
- Glycerophospholipid Synthesis: Two Methods for Adding Polar Head Groups
- Glycerophospholipid Synthesis: Prokaryotes
- Glycerophospholipid Synthesis: Eukaryotes
- Glycerophospholipid Degradation
- Clinical Correlate: Lung Surfactant and Neonatal Respiratory Distress Syndrome (NRDS)
Sphingolipids and their Metabolism
- Sphingolipids: Intro / Overview [copy from Lipids chapter]
- Sphingolipids: Examples [copy from Lipids chapter]
- Sphingolipids: Synthesis
- Sphingolipids: Degradation and Sphingolipidoses - Intro
- Sphingolipids: Degradation and Sphingolipidoses - Details
- Sphingolipidoses: Tay-Sachs Disease [Lysosomal Storage Disease] [ free YouTube snippet | full free sample video ]
- Sphingolipidoses: Niemann-Pick Disease [Lysosomal Storage Disease]
- Sphingolipidoses: Gaucher Disease [Lysosomal Storage Disease]
- Sphingolipidoses: Krabbe Disease [Lysosomal Storage Disease]
- Sphingolipidoses: Metachromatic Leukodystrophy [Lysosomal Storage Disease]
- Sphingolipidoses: Fabry Disease [Lysosomal Storage Disease]
Eicosanoids and their Metabolism
- Eicosanoids: Intro / Overview [copy from Lipids chapter] [ free YouTube snippet | full free sample video ]
- Eicosanoids: Metabolism and Clinical Relevance
Cholesterol Synthesis and Degradation
- Cholesterol Synthesis: Intro / Overview
- Cholesterol Synthesis: Stage 1 - Mevalonate Synthesis
- Cholesterol Synthesis: Stage 2 - Isopentenyl Pyrophosphate (IPP) Synthesis
- Cholesterol Synthesis: Stage 3 - Squalene Synthesis
- Cholesterol Synthesis: Stage 4 - Squalene Cyclization
- Cholesterol Synthesis: Summary of Reactants and Requirements (Big Picture)
- Cholesterol Degradation
Regulation of Cholesterol Synthesis
- Intro
- Short-Term Control
- Long-Term Control
- Overview / Summary
Bile Acids / Bile Salts and their Metabolism
- Intro, Structure, Function
- Synthesis and Conjugation [ free YouTube snippet | full free sample video ]
- Deconjugation, Reabsorption / Recycling, and Excretion
- Clinical Correlate: Cholelithiasis (Gallstones)
Steroid Hormones and their Metabolism
- Intro to Steroids [copy from Lipids chapter]
- Steroid Hormones: Basic Mechanism of Action
- Steroid Hormone Synthesis in the Adrenal Cortex [ free YouTube snippet | full free sample video ]
- Steroid Hormone Synthesis in the Testes
- Steroid Hormone Synthesis in the Ovaries
- Steroid Hormone Degradation / Excretion
- Clinical Correlate: Congenital Adrenal Hyperplasia (CAH) / Adrenogenital Syndrome
Lipoproteins
- Lipoproteins: Intro
- Lipoproteins: Apoproteins / Apolipoproteins
- Lipoproteins: Chylomicrons
- Lipoproteins: VLDL (Very Low Density Lipoprotein)
- Lipoproteins: IDL (Intermediate Density Lipoprotein)
- Lipoproteins: LDL (Low Density Lipoprotein)
- Lipoproteins: HDL (High Density Lipoprotein)
- LDL Receptor: Receptor Mediated Endocytosis
- LDL Receptor: Hypercholesterolemia and Atherosclerosis
- Lipoproteins: "Good" Cholesterol (HDL) vs "Bad" Cholesterol (LDL)
Hyperlipoproteinemias and Hypolipoproteinemias
- Hyperlipoproteinemia: Type I - [Chylomicronemia]
- Hyperlipoproteinemia: Type IIa - [Familial Hypercholesterolemia]
- Hyperlipoproteinemia: Type IIb - [Familial Combined Hyperlipidemia]
- Hyperlipoproteinemia: Type III - [Familial Dysbetalipoproteinemia AKA Remnant Removal Disease] [ free YouTube snippet | full free sample video ]
- Hyperlipoproteinemia: Type IV - [Familial Hypertriglyceridemia]
- Hyperlipoproteinemia: Type V - [Mixed Hyperlipidemia]
- Hypolipoproteinemia: Abetalipoproteinemia
- Hypolipoproteinemia: Tangier Disease